Assisted Hatching

In the field of assisted reproductive technologies (ART), Assisted Hatching (AH) represents a significant advancement targeted at enhancing the success rates of In Vitro Fertilization (IVF). Archish Fertility & IVF, known for its progressive approach to fertility treatments, integrates Assisted Hatching into its protocols to assist couples facing difficulties with embryo implantation. This exploration provides an in-depth look at the Assisted Hatching process, emphasizing how it is strategically utilized to enhance the likelihood of pregnancy.

Assisted Hatching is a micro-manipulative technique used to create an opening in the protective layer surrounding the embryo. This technique is needed when the zona pellucida is abnormally thick or stiff, conditions often found in older women or embryos that have undergone freezing and thawing, which can impede the natural hatching process necessary for implantation.

Step 1: Selection of Embryos

Before the procedure, embryologists at Archish Fertility & IVF evaluate the embryos under a microscope. They assess the thickness and uniformity of the zona pellucida along with the overall quality and developmental stage of the embryos to determine if Assisted Hatching could be beneficial.

Step 2: Preparation for Hatching

The selected embryos are stabilized under a microscope equipped with micromanipulation instruments. This setup is critical to ensure precision and control during the delicate process.

Step 3: Performing Assisted Hatching

Laser Method: The most used technique at Archish Fertility & IVF involves a controlled and precise laser. This laser gently thins a small area of the zona pellucida or creates a tiny hole. Using a laser minimizes physical contact and reduces the risk of damaging the embryo.

Chemical Method: Alternatively, a mild acidic solution can be applied to a specific area of the zona pellucida to weaken it. This method is less commonly used due to the laser technique’s higher precision and safety profile.

Step 4: Monitoring Post-Hatching

After Assisted Hatching, the embryos are carefully monitored to assess their viability and development. This observation period is crucial to ensure that the embryos usually develop after the procedure.

Step 5: Embryo Transfer

The treated embryos are transferred to the woman’s uterus shortly after Hatching. This timing is critical to synchronize the embryo’s development stage with the uterine lining’s receptivity.

The technique is particularly recommended for:

• Women over the age of 37.
• Couples with a history of failed IVF attempts.
• Embryos with a noticeably thick zona pellucida.
• Cases involving frozen embryos.

While Assisted Hatching can enhance the implantation rates and overall success of IVF treatments, it carries risks such as potential embryo damage and a slightly increased likelihood of monozygotic twinning. These risks underscore the importance of performing Assisted Hatching in a highly specialized and controlled environment like Archish Fertility & IVF, where precision and patient safety are paramount.